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Occlusion pressure as a measure of respiratory center output in conscious man. Respir Physiol. Dres M, Dube BP, Mayaux J, Delemazure J, Reuter D, Brochard L, Similowski T, Demoule A.

Coexistence and impact of limb muscle and diaphragm weakness at time of liberation from mechanical ventilation in medical intensive care unit patients.

Chao DC, Scheinhorn DJ, Stearn-Hassenpflug M. Patient—ventilator trigger asynchrony in prolonged mechanical ventilation.

Piquilloud L, Tassaux D, Bialais E, et al. Neurally adjusted ventilatory assist NAVA improves patient—ventilator interaction during non-invasive ventilation delivered by face mask.

Blanch L, Villagra A, Sales B, Montanya J, Lucangelo U, Lujan M, Garcia-Esquirol O, Chacon E, Estruga A, Oliva JC, et al. Asynchronies during mechanical ventilation are associated with mortality.

Demoule A, Clavel M, Rolland-Debord C, Perbet S, Terzi N, Kouatchet A, Wallet F, Roze H, Vargas F, Guerin C, Dellamonica J, Jaber S, Brochard L, Similowski T.

Neurally adjusted ventilatory assist as an alternative to pressure support ventilation in adults: a French multicentre randomized trial. Colombo D, Cammarota G, Bergamaschi V, De Lucia M, Corte FD, Navalesi P.

Physiologic response to varying levels of pressure support and neurally adjusted ventilatory assist in patients with acute respiratory failure.

Download references. All the data are recorded in our institution. Original data are available from the corresponding author on reasonable request.

Department of Anaesthesiology and Critical Care Unit, University Hospital of Toulouse, , Toulouse Cedex 9, France. Conception and design: BG, LC, OL, JMC, and VM.

Analysis and interpretation: LC, JMC, BG, OL, TR, CD and VM. Drafting the manuscript for important intellectual content: BG, OL, AR, CD, SR, TS, and FVB.

All authors read and approved the final manuscript. Correspondence to Olivier Lamouret. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Open Access This article is distributed under the terms of the Creative Commons Attribution 4. Reprints and Permissions.

Lamouret, O. Neurally adjusted ventilatory assist NAVA versus pressure support ventilation: patient-ventilator interaction during invasive ventilation delivered by tracheostomy.

Crit Care 23, 2 Download citation. Received : 29 August Accepted : 04 December Published : 07 January Skip to main content.

Search all BMC articles Search. Download PDF. Abstract Background Prolonged weaning is a major issue in intensive care patients and tracheostomy is one of the last resort options.

Methods We performed a prospective, sequential, non-randomized and single-centre study. Results Among the 61 patients analysed, the total AI was lower in NAVA than in PSV mode: 2.

Conclusion NAVA appears to be a promising ventilator mode in tracheotomised patients, especially for those requiring prolonged weaning due to the decrease in asynchronies.

Introduction Difficult weaning from ventilator support was defined by the consensus conference published in the European Respiratory Journal in [ 1 ].

Material and methods We conducted a prospective, sequential, non-randomized, single-centre study in the ICU of the University Hospital of Rangueil in Toulouse, France.

A moderate PEEP level seems to be an appropriate compromise during the weaning process. The PEEP level was determined for PSV and we used the same level for NAVA.

Data analysis Two independent physicians analysed the recorded data. Full size image. Results Population A total of 66 out of eligible patients Flow chart of the studied population.

Table 1 Main characteristics of the population Full size table. Table 2 Ventilation settings and asynchronies recorded Full size table. Discussion Difficult weaning from ventilator support requires optimal ventilation settings.

Conclusion This is the first study to compare patient-ventilator asynchronies in NAVA and PSV in tracheotomised patients presenting with difficult weaning criteria.

Abbreviations AI: Asynchrony index COPD: Chronic obstructive pulmonary disease Eadi: Electrical activity of the diaphragm ICU: Intensive care unit NAVA: Neurally adjusted ventilatory assist PDW: Predicted body weight PEEP: Positive end-expiratory pressure PSV: Pressure support ventilation SAPS: Simplified Acute Physiology Score VAP: Ventilator-associated pneumonia VT: Tidal volume.

References 1. Acknowledgements We would like to thank the medical and paramedical teams from Rangueil Critical Care Unit. Funding None.

Availability of data and materials All the data are recorded in our institution. View author publications.

Ethics declarations Ethics approval and consent to participate The study was approved by the Ethics Research Committee of our institution No.

Consent for publication Not applicable. Competing interests The authors declare that they have no competing interests. Rights and permissions Open Access This article is distributed under the terms of the Creative Commons Attribution 4.

About this article. Design for either Ductility Class High H or Medium M of EC8 is much more cost-effective than design for Ductility Class Low L , even in moderate seismicity.

It is also much more cost-effective than design to the Greek national codes. This is a preview of subscription content, log in to check access.

Rent this article via DeepDyve. CEN Part 1: General rules, seismic actions and rules for buildings.

Formal Vote Version Stage 49 , November Chapter 4: fib Bulletin No. Litton, R. A Contribution to the Analysis of Concrete Structures under Cyclic Loading.

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